DCTN3

BT-AP09074

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human DCTN3

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes the smallest subunit of dynactin| a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions| including ER-to-Golgi transport| the centripetal movement of lysosomes and endosomes| spindle formation| cytokinesis| chromosome movement| nuclear positioning| and axonogenesis. This subunit| like most other dynactin subunits| exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil| and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.

Human: O75935; Mouse: Q9Z0Y1;

20460

Human: 11258; Mouse: 53598

DCTN3

Cell biology; Signal transduction

DCTN3