BT-AP00032 WB,IHC-p,ELISA
Description
Cat.No. BT-AP00032 Size: 100ul/50ul/20ul Datasheet Request
Product Information
Clonallity: Polyclonal
Applications: WB,IHC-p, ELISA
Source: Rabbit
Immunogen: Synthesized peptide derived from human protein. AA range: 170-250
Protein Name: Band 4.1-like protein 2
Species reactivity: human
Concentration: 1 mg/ml
Observed molecular weight: 112 kDa
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Recommended Dilution:
WB: 1:500 – 1:2000
IHC: 1:100 – 1: 300
ELISA: 1: 40000
Not yet tested in other applications
Synonyms: EPB41L2; Band 4.1-like protein 2; Generally expressed protein 4.1; 4.1G
Storage:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C.
Background：
The 4.1 gene family encodes a group of multifunctional cytoskeletal proteins (4.1R, 4.1G, 4.1N and 4.1B), which are predominantly expressed in the nervous system. 4.1G is a protein that stabilizes spectrin-actin interactions and is associated with hereditary elliptocytosis. Red blood cell 4.1, designated 4.1R, is a multifunctional protein that is essential for maintaining erythrocyte shape and membrane mechanical properties. Both 4.1R and 4.1G are distributed in a unique pattern in the cerebellum and are believed to modulate the membrane mechanical properties of neuronal cells by promoting fodrin/actin association. 4.1N and 4.1B, designated EPB41L1 and EPB41L3, respectively, are strongly expressed in the brain. Antibodies to 4.1N have been reported to detect mulitple forms, each enriched in postsynaptic density preparations relative to brain homogenate. Antibodies to 4.1B have been reported to detect two forms.