4.1R Polyclonal Antibody

BT-AP00033                                      WB,ELISA

Description

Cat.No. BT-AP00033  Size: 100ul/50ul/20ul    Datasheet Request  

Product Information

Clonallity: Polyclonal

Applications: WB, ELISA

Source: Rabbit

Immunogen: Synthesized peptide derived from human protein. AA range: 170-250

Protein Name: Protein 4.1

Species reactivity: human, mouse

Concentration: 1 mg/ml

Observed molecular weight: 60 kDa

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Recommended Dilution:

WB: 1:500 – 1:2000

ELISA: 1:5000

Not yet tested in other applications

Synonyms: EPB41; E41P; Protein 4.1; P4.1; 4.1R; Band 4.1; EPB4.1

Storage:

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C.

Background:

The erythrocyte membrane protein band 4. encoded by EPB41, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.