Cat.No. BT-AP01008 Size: 100ul/50ul/20ul Datasheet Request
Immunogen: The antiserum was produced against synthesized peptide derived from human BUB1. AA range:251-300
Protein Name: Mitotic checkpoint serine/threonine-protein kinase BUB1
Species reactivity: human, mouse
Concentration: 1 mg/ml
Molecular weight: 122375 Da
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
BUB1; BUB1L; Mitotic checkpoint serine/threonine-protein kinase BUB1; hBUB1; BUB1A
IHC: 1:100 – 1:300
ELISA: 1: 10000
Not yet tested in other applications
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C.
BUB1 mitotic checkpoint serine/threonine kinase(BUB1) Homo sapiens This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.