BUB1B Polyclonal Antibody

BT-AP01010                                      WB,ELISA

Description

Cat.No. BT-AP01010  Size: 100ul/50ul/20ul    Datasheet Request  

Product Information

Clonallity: Polyclonal

Applications: WB,ELISA

Source: Rabbit

Immunogen: Synthesized peptide derived from part region of human protein

Protein Name: Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

Species reactivity: human, mouse

Concentration: 1 mg/ml

Observed molecular weight: 115 kDa

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Synonyms:

MAD3/BUB1-related protein kinase;hBUBR1;Mitotic checkpoint kinase MAD3L;Protein SSK1

Recommended Dilution:

WB: 1:500 – 1:2000

ELISA: 1:5000 – 1:20000

Not yet tested in other applications

Storage:

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C.

Background:

BUB1 mitotic checkpoint serine/threonine kinase B(BUB1B) Homo sapiens This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.