BubR1 Polyclonal Antibody

BT-AP01012                                      WB,ELISA

Description

Cat.No. BT-AP01012  Size: 100ul/50ul/20ul    Datasheet Request  

Product Information

Clonallity: Polyclonal

Applications: WB,ELISA

Source: Rabbit

Immunogen: The antiserum was produced against synthesized peptide derived from human BUB1B. AA range:341-390

Protein Name: Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

Species reactivity: human, mouse

Concentration: 1 mg/ml

Observed molecular weight: 130 kDa

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Synonyms:

BUB1B; BUBR1; MAD3L; SSK1; Mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MAD3/BUB1-related protein kinase; hBUBR1; Mitotic checkpoint kinase MAD3L; Protein SSK1

Recommended Dilution:

WB: 1:500 – 1:2000

ELISA: 1: 20000

Not yet tested in other applications

Storage:

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C.

Background

BUB1 mitotic checkpoint serine/threonine kinase B(BUB1B) Homo sapiens This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.