C/EBP Zeta Polyclonal Antibody

BT-AP01023                                      WB,IHC-p,IF,ELISA

Description

Cat.No. BT-AP01023  Size: 100ul/50ul/20ul    Datasheet Request  

Product Information

Clonallity: Polyclonal

Applications: WB,IHC-p,IF,ELISA

Source: Rabbit

Immunogen: The antiserum was produced against synthesized peptide derived from human CEBPZ. AA range:1-50

Protein Name: CCAAT/enhancer-binding protein zeta

Species reactivity: Human

Concentration: 1 mg/ml

Observed molecular weight: 120 kDa

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Synonyms:

CEBPZ; CBF2; CCAAT/enhancer-binding protein zeta; CCAAT-box-binding transcription factor; CBF; CCAAT-binding factor

Recommended Dilution:

WB: 1:500 – 1:2000

IHC:1:100 -1:300

IF:1:200 – 1:1000

ELISA: 1:20000

Not yet tested in other applications

Storage:

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C.

Background:

CCAAT/enhancer binding protein zeta(CEBPZ) Homo sapiens This gene belongs to the CEBP family. The encoded protein plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes. The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner. The protein is also involved in cell growth and differentiation, particularly, hematopoietic differentiation. Methylation of the promoter of this gene or mutations within the gene may be correlated with occurance of acute myeloid leukemia (AML).