C11B2 Polyclonal Antibody

BT-AP01024                                      WB,ELISA

Description

Cat.No. BT-AP01024  Size: 100ul/50ul/20ul    Datasheet Request  

Product Information

Clonallity: Polyclonal

Applications: WB, ELISA

Source: Rabbit

Immunogen: Synthesized peptide derived from human protein at AA range: 280-360

Protein Name: Cytochrome P450 11B2, mitochondrial

Species reactivity: Human, mouse, rat

Concentration: 1 mg/ml

Observed molecular weight: 55 kDa

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Synonyms

Aldosterone synthase;ALDOS;EC 1.14.15.4;EC 1.14.15.5;Aldosterone-synthesizing enzyme;CYPXIB2;Cytochrome P-450Aldo;Cytochrome P-450C18;Steroid 18-hy

Recommended Dilution:

WB: 1:500 – 1:2000

ELISA: 1:5000 – 1:20000

Not yet tested in other applications

Storage:

Store at -20 °C for one year. Avoid repeated fre eze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C.

Background

Cytochrome P450 family 11 subfamily B member 2(CYP11B2) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.