C8 β Polyclonal Antibody

BT-AP01053                                      WB,ELISA

Description

Cat.No. BT-AP01053  Size: 100ul/50ul/20ul    Datasheet Request  

Product Information

Clonallity: Polyclonal

Applications: WB,ELISA

Source: Rabbit

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human C8B. AA range:371-420

Protein Name: C8 beta

Species reactivity: Human,rat

Concentration: 1 mg/ml

Observed molecular weight: 70 kDa

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Recommended Dilution:

WB: 1:500 – 1:2000

ELISA: 1:10000- 1:20000

Not yet tested in other applications

Synonyms: Complement component C8 beta chain;Complement component 8 subunit beta

Storage:

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C.

Background:
complement C8 beta chain(C8B) Homo sapiens This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants.