CAC1E Polyclonal Antibody

BT-AP01082                                      IHC-p

Description

Cat.No. BT-AP01082  Size: 100ul/50ul/20ul    Datasheet Request  

Product Information

Clonallity: Polyclonal

Applications: IHC-p

Source: Rabbit

Immunogen: Synthesized peptide derived from human protein at AA range: 370-450

Protein Name: Brain calcium channel II;BII;Calcium channel, L type, alpha-1 polypeptide, isoform 6;Voltage-gated calcium channel subunit alpha Cav2.3

Species reactivity: Human, mouse,rat

Concentration: 1 mg/ml

Observed molecular weight: 254 kDa

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Recommended Dilution:

IHC: 1:500 – 1:300

Not yet tested in other applications

Storage:

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C.

Background:

calcium voltage-gated channel subunit alpha1 E(CACNA1E) Homo sapiens Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the ‘high-voltage activated’ group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.