Cadherin-16 Polyclonal Antibody

BT-AP01096                                      WB,IHC-p,IF,ELISA

Description

Cat.No. BT-AP01096  Size: 100ul/50ul/20ul    Datasheet Request  

Product Information

Clonallity: Polyclonal

Applications: WB,IHC-p,IF,ELISA

Source: Rabbit

Immunogen: The antiserum was produced against synthesized peptide derived from human CDH16. AA range:780-829

Protein Name: Cadherin-16

Species reactivity: Human

Concentration: 1 mg/ml

Observed molecular weight: 90 kDa

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Synonyms

CDH16; Cadherin-16; Kidney-specific cadherin; Ksp-cadherin

Recommended Dilution:

WB: 1:500 – 1:2000

IHC: 1:100 – 1:300

IF: 1:200 – 1:1000

ELISA: 1:10000

Not yet tested in other applications

Storage:

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C.

Background:

cadherin 16(CDH16) Homo sapiens This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.