Cadherin-23 Polyclonal Antibody

BT-AP01101                                      IF,ELISA

Description

Cat.No. BT-AP01101  Size: 100ul/50ul/20ul    Datasheet Request  

Product Information

Clonallity: Polyclonal

Applications: IF,ELISA

Source: Rabbit

Immunogen: The antiserum was produced against synthesized peptide derived from human CDH23. AA range:61-110

Protein Name: Cadherin-23

Species reactivity: Human, mouse,rat

Concentration: 1 mg/ml

Molecular weight: 369525 Da

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Synonyms: CDH23; KIAA1774; KIAA1812; Cadherin-23; Otocadherin

Recommended Dilution:

IF: 1:200 – 1:1000

ELISA: 1:10000

Not yet tested in other applications

Storage:

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C.

Background:

Cadherin related 23(CDH23) Homo sapiens This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described.