Cat.No. BT-AP01105 Size: 100ul/50ul/20ul Datasheet Request
Immunogen: The antiserum was produced against synthesized peptide derived from human CDH8. AA range:491-540
Protein Name: Cadherin-8
Species reactivity: human, mouse,rat
Concentration: 1 mg/ml
Observed molecular weight: 90 kDa
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
WB: 1:500 – 1:2000
IHC: 1:100 – 1: 300
IF: 1:200 -1:1000
Not yet tested in other applications
Synonyms: CDH8; Cadherin-8
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C.
Cadherin 8(CDH8) Homo sapiens This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein’s homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.