Cat.No. BT-AP01686 Size: 100ul/50ul/20ul Datasheet Request
Immunogen: Synthesized peptide derived from human protein at AA range: 10-90
Protein Name: Centromere protein R
Species reactivity: human
Concentration: 1 mg/ml
Observed molecular weight: 19 kDa
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
WB: 1:500 – 1:2000
ELISA: 1:5000 – 1:20000
Not yet tested in other applications
Synonyms: CENP-R;Beta-3-endonexin;Integrin beta-3-binding protein;Nuclear receptor-interacting factor 3
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C.
Integrin subunit beta 3 binding protein(ITGB3BP) Homo sapiens This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.