CENPR Polyclonal Antibody

BT-AP01686                                      WB,ELISA

Description

Cat.No. BT-AP01686  Size: 100ul/50ul/20ul    Datasheet Request  

Product Information

Clonallity: Polyclonal

Applications: WB,ELISA

Source: Rabbit

Immunogen: Synthesized peptide derived from human protein at AA range: 10-90

Protein Name: Centromere protein R

Species reactivity: human

Concentration: 1 mg/ml

Observed molecular weight: 19 kDa

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Recommended Dilution:

WB: 1:500 – 1:2000

ELISA: 1:5000 – 1:20000

Not yet tested in other applications

Synonyms: CENP-R;Beta-3-endonexin;Integrin beta-3-binding protein;Nuclear receptor-interacting factor 3

Storage:

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C.

Background:

Integrin subunit beta 3 binding protein(ITGB3BP) Homo sapiens This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.