BT-AP01687 WB,ELISA
Description
Cat.No. BT-AP01687 Size: 100ul/50ul/20ul Datasheet Request
Product Information
Clonallity: Polyclonal
Applications: WB,ELISA
Source: Rabbit
Immunogen: Synthesized peptide derived from human protein at AA range: 70-150
Protein Name: Centromere protein S
Species reactivity: human
Concentration: 1 mg/ml
Observed molecular weight: 15 kDa
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Recommended Dilution:
WB: 1:500 – 1:2000
ELISA: 1:5000 – 1:20000
Not yet tested in other applications
Synonyms: CENP-S;Apoptosis-inducing TAF9-like domain-containing protein 1;FANCM-interacting histone fold protein 1;Fanconi anemia-associated polypeptide of 16 kDa
Storage:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C.
Background：
Centromere protein S(CENPS) Homo sapiens This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF(II)31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex, the APITD1/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex, and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants.