Cat.No. BT-AP01698 Size: 100ul/50ul/20ul Datasheet Request
Immunogen: The antiserum was produced against synthesized peptide derived from human CEP55. AA range:81-130
Protein Name: Centrosomal protein of 55 kDa
Species reactivity: human
Concentration: 1 mg/ml
Observed molecular weight: 54 kDa
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
WB: 1:500 – 1:2000
IHC: 1:100 – 1: 300
Not yet tested in other applications
Synonyms: CEP55; C10orf3; URCC6; Centrosomal protein of 55 kDa; Cep55; Up-regulated in colon cancer 6
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C.
ATF2 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein (activating transcription factor 2) has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell’s DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for ATF2.