HSP27 Monoclonal Antibody(Mix-mA)

BT-MCA0832                                      WB,IHC-p

Description

Cat.No. BT-MCA0832  Size: 100ul/50ul/20ul    Datasheet Request  

Product Information

Clonallity: Polyclonal

Applications: WB,IHC-p

Source: Mouse

Immunogen: Recombinant Protein of HSP27.

Protein Name: Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27).

Species reactivity: Human

Concentration: 1 mg/ml

ConcentraObserved molecular weight: 27 kDa

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification:

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

Recommended Dilution:

WB: 1:1000 – 1:3000

IHC: 1:50 – 1:200

Not yet tested in other applications

Synonyms: Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)

Storage:

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C.

Background:

The protein encoded by HSPB1 (heat shock protein family B (small) member 1) is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in HSPB1 are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).