HSP60 (ABT-HSP60) Monoclonal Antibody

BT-MCA0834                                      IHC-p,IF

Description

Cat.No. BT-MCA0834  Size: 100ul/50ul/20ul    Datasheet Request  

Product Information

Clonallity: Polyclonal

Applications: IHC-p,IF

Source: Mouse

Immunogen: Synthesized peptide derived from human HSP60.

Protein Name: 60 kDa heat shock protein, mitochondrial (60 kDa chaperonin) (Chaperonin 60) (CPN60) (Heat shock protein 60) (HSP-60) (Hsp60) (HuCHA60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein).

Species reactivity: Human

Concentration: 1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification:

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Recommended Dilution:

IHC-p: 1:100 – 500

IF: 1:500 – 200

Not yet tested in other applications

Storage:

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C.

Background:

HSPD1 encodes a member of the chaperonin family. 60 kDa heat shock protein mitochondrial may function as a signaling molecule in the innate immune system. 60 kDa heat shock protein mitochondrial is essential for the folding and assembly of newly imported proteins in the mitochondria. HSPD1 is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.