IGF-2 (ABT-IGF2) Monoclonal Antibody

BT-MCA0871                                      IHC-p

Description

Cat.No. BT-MCA0871  Size: 100ul/50ul/20ul    Datasheet Request  

Product Information

Clonallity: Polyclonal

Applications: IHC-p

Source: Mouse

Immunogen: Synthesized peptide derived from human IGF-2.

Protein Name: Insulin-like growth factor II (IGF-II) (Somatomedin-A) [Cleaved into: Insulin-like growth factor II; Insulin-like growth factor II.

Species reactivity: Human

Concentration: 1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification:

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Recommended Dilution:

IHC-p: 1:100 – 500

Not yet tested in other applications

Storage:

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C.

Background:

insulin like growth factor 2(IGF2) Homo sapiens This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5′ region overlaps the INS gene and the 3′ region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.