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Home > Product > ELISA Kit > Human Potassium Channel Subfamily K Member 18, KCNK18 ELISA Kit

Human Potassium Channel Subfamily K Member 18, KCNK18 ELISA Kit

Human Potassium Channel Subfamily K Member 18, KCNK18 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 0.019ng/ml

Detection range: 0.05-10ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 0.019ng/ml

Detection range: 0.05-10ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

Potassium Channel subfamily K member 18

Code

E1789Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

0.019ng/ml

Detection range

0.05-10ng/ml

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Outward rectifying potassium channel. Produces rapidly activating outward rectifier K+ currents. May function as background potassium channel that sets the resting membrane potential. Channel activity is directly activated by calcium signal. Activated by the G(q)-protein coupled receptor pathway. The calcium signal robustly activates the channel via calcineurin, whereas the anchoring of 14-3-3/YWHAH interferes with the return of the current to the resting state after activation. Inhibited also by arachidonic acid and other naturally occurring unsaturated free fatty acids. Channel activity is also enhanced by volatile anesthetics, such as isoflurane. Appears to be the primary target of hydroxy-alpha-sanshool, an ingredient of Schezuan pepper. May be involved in the somatosensory function with special respect to pain sensation (By similarity).

UniProt accession

MASS(Da)

43,671

GeneID

338567

Synonyms

K2p18.1;KCNK18;MGR13;Potassium Channel subfamily K member 18;TRESK;TRESK2;TRESK-2;TRIK;TWIK-related individual potassium Channel;TWIK-related spinal cord potassium Channel

Gene names

KCNK18

Research area

Neuroscience

Target protein

KCNK18

Components

Components Quantity
Pre-coated ELISA plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E1789Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
6.4ng/ml 2.211 2.252 2.202
2.294
3.2ng/ml 1.233 1.218 1.167
1.202
1.6ng/ml 0.748 0.69 0.639
0.631
0.8ng/ml 0.525 0.512 0.461
0.498
0.4ng/ml 0.247 0.228 0.178
0.209
0ng/ml 0.04 0.05 0
0.06

Precision

We measured random samples of E1789Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 1.44 0.09 6.34
Intra-Assay 2 18 3.12 0.19 6.14
Intra-Assay 3 18 3.19 0.11 3.49

Protocols

References

Customer reviews and Q&As

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Associated products

  • Size

    Code

    Price

  • 48T

    E1789Hu

    $320.00

  • 96T

    E1789Hu

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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