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Home > Product > ELISA Kit > Mouse Interleukin 11, IL-11 ELISA Kit

Mouse Interleukin 11, IL-11 ELISA Kit

Mouse Interleukin 11, IL-11 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 0.43ng/L

Detection range: 1-300ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Mouse

Product Summary

Size: 48T,96T

Sensitivity: 0.43ng/L

Detection range: 1-300ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Mouse

Product overview

Full product name

Interleukin 11

Code

E0021Mo

Assay type

Sandwich

Size

48T,96T

Sensitivity

0.43ng/L

Detection range

1-300ng/L

Sample type

Serum, plasma, cell culture supernates

Species

Mouse

Storage

2-8ºC

Assay time

1h 30m

Background

Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed: 8913282). Also promotes the proliferation of hepatocytes in response to liver damage (PubMed: 22253262). Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation, also in the context of various cancers (PubMed: 10026196, PubMed: 23948300). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3 (PubMed: 23948300, PubMed: 22253262). The interaction with the membrane-bound IL11RA and IL6ST stimulates 'classic signaling', whereas the binding of IL11 and soluble IL11RA to IL6ST stimulates 'trans-signaling' (By similarity).

UniProt accession

MASS(Da)

21,522

GeneID

16156

Synonyms

IL 11;IL11;IL-11;Interleukin-11

Gene names

IL11

Research area

Immunology

Target protein

IL11

Components

Components Quantity
Pre-coated ELISA Plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E0021Mo are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
160ng/L 2.031 2.105 2.065
2.18
80ng/L 1.386 1.421 1.381
1.457
40ng/L 0.824 0.82 0.78
0.816
20ng/L 0.533 0.517 0.476
0.5
10ng/L 0.237 0.273 0.233
0.309
0ng/L 0.033 0.04 0
0.048

Precision

We measured random samples of E0021Mo within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 61.4 4.22 6.9
Intra-Assay 2 18 107.8 5.58 5.2
Intra-Assay 3 18 13.5 0.71 5.2

Protocols

References

Customer reviews and Q&As

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  • Size

    Code

    Price

  • 48T

    E0021Mo

    $320.00

  • 96T

    E0021Mo

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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