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Home > Product > ELISA Kit > Human Growth Differentiation Factor 15, GDF15 ELISA Kit

Human Growth Differentiation Factor 15, GDF15 ELISA Kit

Human Growth Differentiation Factor 15, GDF15 ELISA Kit

Product Summary

Size: 96T,48T

Sensitivity: 5.57ng/L

Detection range: 10-3000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 96T,48T

Sensitivity: 5.57ng/L

Detection range: 10-3000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

Growth Differentiation Factor 15

Code

E0037Hu

Assay type

Sandwich

Size

96T,48T

Sensitivity

5.57ng/L

Detection range

10-3000ng/L

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed: 28953886, PubMed: 28846097, PubMed: 28846098, PubMed: 28846099, PubMed: 23468844, PubMed: 29046435). Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PubMed: 28953886, PubMed: 28846097, PubMed: 28846098, PubMed: 28846099). It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed: 28953886). On hepatocytes, inhibits growth hormone signaling (By similarity).

UniProt accession

MASS(Da)

34,140

GeneID

9518

Synonyms

GDF 15;GDF15;GDF-15;Growth/differentiation factor 15;Macrophage inhibitory cytokine 1;MIC-1;NAG-1;NRG-1;NSAID-activated gene 1 protein;NSAID-regulated gene 1 protein;Placental bone morphogenetic protein;Placental TGF-beta;Prostate differentiation factor;

Gene names

GDF15

Research area

Signal Transduction; Cardiovascular

Target protein

GDF15

Components

Components Quantity
Pre-coated ELISA Plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E0037Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
1600ng/L 2.076 2.016 1.983
1.956
800ng/L 1.151 1.157 1.125
1.163
400ng/L 0.561 0.573 0.54
0.585
200ng/L 0.271 0.282 0.25
0.294
100ng/L 0.072 0.121 0.089
0.17
0ng/L 0.033 0.032 0
0.032

Precision

We measured random samples of E0037Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 248.1 9.75 3.9
Intra-Assay 2 18 1244.8 39.23 3.2
Intra-Assay 3 18 603 28.98 4.8

Protocols

References (2)

Growth differentiation factor 15: an emerging diagnostic biomarker of liver fibrosis in chronic hepatitis C patients
The association between growth differentiation factor-15, erythroferrone, and iron status in thalassemic patients

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  • Size

    Code

    Price

  • 96T

    E0037Hu

    $458.00

  • 48T

    E0037Hu

    $320.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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