Product name
Recombinant Human FABP2 protein
Code
CD01836
Biological activity
Data Not Available.
Endotoxin
Less than 0.1 EU/μg of rHuFABP2 as determined by LAL method.
Synonyms
FABP2, FABPI, I-FABPHuman
Sequence
AFDSTWKVDR SENYDKFMEK MGVNIVKRKL AAHDNLKLTI TQEGNKFTVK ESSAFRNIEV VFELGVTFNY NLADGTELRG TWSLEGNKLI GKFKRTDNGN ELNTVREIIG DELVQTYVYE GVEAKRIFKK D
Uniprot Accession
Molecular Weight
Approximately 15.1 kDa, a single non-glycosylated polypeptide chain containing 131 amino acids.
Formulation
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Background
FABP2, also called intestinal-type fatty acid-binding protein (I-FABP or FABPI) and gut FABP (gFABP), is a member of the cytosolic fatty acid binding protein family. FABP2 mediates the absorption and intracellular transport of dietary long-chain fatty acids. Genetic variations of FABP2 are implicated in obesity and Type II diabetes. Human FABP2 shares 86 %, 85 %, and 82 % a.a. sequence identity with canine, porcine, and rat FABP2, respectively.
Storage
-20ºC
Research area
Cardiovascular
