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Home > Product > Antibody > IGF-IR Monoclonal Antibody

IGF-IR Monoclonal Antibody

IGF-IR Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Insulin-like growth factor 1 receptor

Code

BT-MCA0099

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of IGF-IR expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 3480

Synonyms

IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221

Research area

Cancer; Signal Transduction; Developmental Biology

Target protein

IGF1R

Recommended dilution

Application Dilution
ELISA 1:10000
IHC 1:200 - 1:1000
WB 1:500 - 1:2000

Images

Western Blot analysis using IGF-IR Monoclonal antibody against truncated IGF-IR recombinant protein.
Immunohistochemistry analysis of paraffin-embedded human gastric adenocarcinoma(A), colon adenocarcinoma(B), endometrial carcinoma(uterus)(C), ovary adenocarcinoma(D), lung squamous cell carcinoma(E), stomach epithelium mucosae(F), showing membrane locali

Protocols

References

Customer reviews and Q&As

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

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Lead time: Within one week

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