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Home > Product > Antibody > ATF-2 Monoclonal Antibody

ATF-2 Monoclonal Antibody

ATF-2 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human, Mouse

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human,Mouse

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Cyclic AMP-dependent transcription factor ATF-2

Code

BT-MCA0189

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human ATF-2 expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro| thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 1386; Mouse: 1.00048e+008

Synonyms

ATF2; CREB2; CREBP1; Cyclic AMP-dependent transcription factor ATF-2; cAMP-dependent transcription factor ATF-2; Activating transcription factor 2; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding pro

Research area

Epigenetics and nuclear signaling; Immunology

Target protein

ATF2

Recommended dilution

Application Dilution
ELISA 1:10000
IHC 1:200 - 1:1000
WB 1:500 - 1:2000

Images

Western Blot analysis using ATF-2 Monoclonal antibody against NIH/3T3 cell lysate.
Immunohistochemistry analysis of paraffin-embedded lung cancer (left) and brain tissues (right) with DAB staining using ATF-2 Monoclonal antibody.

Protocols

References

Customer reviews and Q&As

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

Add to Cart

Lead time: Within one week

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