Tel:86 021 3100 7137

Publish and get free product : share with us your publications using BT LAB product and get free products.
Home > Product > Antibody > Catenin-Beta Monoclonal Antibody

Catenin-Beta Monoclonal Antibody

Catenin-Beta Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, IHC-p, IF, ICC, FCM, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB, IHC-p, IF, ICC, FCM, ELISA

Product overview

Full product name

Catenin beta-1

Code

BT-MCA0261

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human Catenin-Beta expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 1499

Synonyms

CTNNB1; CTNNB; OK; SW-cl.35; Catenin beta-1; Beta-catenin

Research area

Epigenetics and nuclear signaling; Neuroscience; Signal transduction; Cancer; Cardiovascular; Stem cells

Target protein

CTNNB1

Recommended dilution

Application Dilution
FC 1:200 - 1:400
IF 1:200 - 1:1000
IHC 1:200 - 1:1000
WB 1:500 - 1:2000

Images

Western Blot analysis using Catenin-Beta Monoclonal antibody against CTNNB1-hIgGFc transfected HEK293 cell lysate.
Immunohistochemistry analysis of paraffin-embedded human Placenta tissues with AEC staining using Catenin-Beta Monoclonal antibody.
Immunofluorescence analysis of A549 (left) and SK-BR-3 (right) cells using Catenin-Beta Monoclonal antibody (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
Flow cytometric analysis of A549 cells using Catenin-Beta Monoclonal antibody (green) and negative control (purple).

Protocols

References

Customer reviews and Q&As

No reviews
No reviews

Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

Add to Cart

Lead time: Within one week

We are continuously updating our Antibody catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

Newsletter

Sign up

Newsletter

Sign up