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Home > Product > Antibody > CD276 Monoclonal Antibody

CD276 Monoclonal Antibody

CD276 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, IHC-p, IF, FCM, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB, IHC-p, IF, FCM, ELISA

Product overview

Full product name

CD276 antigen

Code

BT-MCA0293

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human CD276 expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 80381

Synonyms

CD276; B7H3; PSEC0249; CD276 antigen; 4Ig-B7-H3; B7 homolog 3; B7-H3; Costimulatory molecule; CD antigen CD276

Research area

Immunology; Cancer; Stem cells

Target protein

CD276

Recommended dilution

Application Dilution
ELISA 1:10000
FC 1:200 - 1:400
IHC 1:200 - 1:1000
WB 1:500 - 1:2000

Images

Western Blot analysis using CD276 Monoclonal antibody against HEK293 (1) and CD276-hIgGFc transfected HEK293 (2) cell lysate.
Immunohistochemistry analysis of paraffin-embedded cervical cancer tissues (left) and ovarian cancer tissues (right) with DAB staining using CD276 Monoclonal antibody.
Flow cytometric analysis of PC-3 cells using CD276 Monoclonal antibody (green) and negative control (purple).

Protocols

References

Customer reviews and Q&As

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

Add to Cart

Lead time: Within one week

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