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Home > Product > Antibody > Cdk4 Monoclonal Antibody

Cdk4 Monoclonal Antibody

Cdk4 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human, Mouse, Rat, Dog, Pig

Applications: WB

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human,Mouse,Rat,Dog,Pig

Applications: WB

Product overview

Full product name

Cell division protein kinase 4

Code

BT-MCA0330

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant human Cdk4 protein fragments expressed in E.coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Storage

-20°C for one year

Background

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 1019; Mouse: 12567; Rat: 94201

Synonyms

CDK4; Cyclin-dependent kinase 4; Cell division protein kinase 4; PSK-J3

Research area

Epigenetics and nuclear signaling; Cancer

Target protein

CDK4

Recommended dilution

Application Dilution
WB 1:1000 - 1:2000

Images

Western Blot analysis using Cdk4 Monoclonal antibody against HeLa, LNCAP, F9 cell lysate.

Protocols

References

Customer reviews and Q&As

No reviews
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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

Add to Cart

Lead time: Within one week

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