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Home > Product > Antibody > Fibulin-5 Monoclonal Antibody

Fibulin-5 Monoclonal Antibody

Fibulin-5 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB, ELISA

Product overview

Full product name

Fibulin-5

Code

BT-MCA0543

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of Fibulin-5 expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 10516

Synonyms

FBLN5; DANCE; Fibulin-5; FIBL-5; Developmental arteries and neural crest EGF-like protein; Dance; Urine p50 protein; UP50

Research area

Signal transduction; Cardiovascular

Target protein

FBLN5

Recommended dilution

Application Dilution
ELISA 1:10000
WB 1:500 - 1:2000

Images

Western Blot analysis using Fibulin-5 Monoclonal antibody against truncated fibulin5 recombinant protein (1) and HeLa cell lysate (2).

Protocols

References

Customer reviews and Q&As

No reviews
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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

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Lead time: Within one week

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