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Home > Product > Antibody > HDAC3 Monoclonal Antibody

HDAC3 Monoclonal Antibody

HDAC3 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Histone deacetylase 3

Code

BT-MCA0668

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of HDAC3 (aa224-428) expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 8841

Synonyms

HDAC3; Histone deacetylase 3; HD3; RPD3-2; SMAP45

Research area

Epigenetics and nuclear signaling; Stem cells; Cancer; Metabolism

Target protein

HDAC3

Recommended dilution

Application Dilution
ELISA 1:10000
IHC 1:200 - 1:1000
WB 1:500 - 1:2000

Images

Western Blot analysis using HDAC3 Monoclonal antibody against truncated Trx-HDAC3 recombinant protein (1) full length HDAC3-hIgGFc (aa1-428) transfected CHO-K1 cell lysate(2) and HeLa cell lysate (3).
Immunohistochemistry analysis of paraffin-embedded human esophagus cancer (left) and breast carcinoma tissue (right), showing nuclear localization with DAB staining using HDAC3 Monoclonal antibody.

Protocols

References

Customer reviews and Q&As

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

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Lead time: Within one week

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