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Home > Product > Antibody > HDAC3 Monoclonal Antibody

HDAC3 Monoclonal Antibody

HDAC3 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human, Mouse, Rat, Dog, Pig, Rabbit

Applications: WB

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human,Mouse,Rat,Dog,Pig,Rabbit

Applications: WB

Product overview

Full product name

Histone deacetylase 3

Code

BT-MCA0669

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant human HDAC3 protein fragments expressed in E.coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Storage

-20°C for one year

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 884184578

Synonyms

HDAC3; Histone deacetylase 3; HD3; RPD3-2; SMAP45

Research area

Epigenetics and nuclear signaling; Stem cells; Cancer; Metabolism

Target protein

HDAC3

Recommended dilution

Application Dilution
WB 1:1000 - 1:2000

Images

Western Blot analysis using HDAC3 Monoclonal antibody against THP-1. LNCAP, MCF7, PC12. 293. Jurkat, 3T3. HeLa cell lysate.

Protocols

References

Customer reviews and Q&As

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

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Lead time: Within one week

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