IRE1 Alpha Monoclonal Antibody

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Home > Product > Antibody > IRE1 Alpha Monoclonal Antibody

IRE1 Alpha Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Serine,threonine-protein kinase,endoribonuclease IRE1

Code

BT-MCA0787

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human IRE1α (aa282-433) expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.

Uniprot accession

Human: O75460; Mouse: Q9EQY0;

Molecular weight

N/A

Gene ID

Human: 2081

Synonyms

ERN1; IRE1; Serine; threonine-protein kinase; endoribonuclease IRE1; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; hIRE1p; Ire1-alpha; IRE1a

Research area

Signal transduction

Target protein

ERN1

Recommended dilution

Application	Dilution
ELISA	1:10000
IHC	1:200 - 1:1000
WB	1:500 - 1:2000

Images

Western Blot analysis using IRE1Alpha Monoclonal antibody against Raji (1) A431 (2) Jurkat (3) HeLa(4) and HEK293 (5) cell lysate.

Immunohistochemistry analysis of paraffin-embedded human brain tissue (A) and stomach tissue (B), showing cytoplasmic localization with DAB staining using IRE1Alpha Monoclonal antibody.

Protocols

> Protocol Booklet

References

Customer reviews and Q&As

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Datasheet

Product size

Price

50ul

$180.00
100ul

$300.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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