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Home > Product > Antibody > PP1 Alpha Monoclonal Antibody

PP1 Alpha Monoclonal Antibody

PP1 Alpha Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human, Mouse, Rat, Bovine, Chicken, Pig, Rabbit, Zebrafish

Applications: WB, IF, ICC

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human,Mouse,Rat,Bovine,Chicken,Pig,Rabbit,Zebrafish

Applications: WB, IF, ICC

Product overview

Full product name

Serine,threonine-protein phosphatase PP1-alpha catalytic subunit

Code

BT-MCA1045

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant human PP1α (N-terminus) protein fragments expressed in E.coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Storage

-20°C for one year

Background

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 5499; Mouse: 19045; Rat: 24668

Synonyms

PPP1CA; PPP1A; Serine; threonine-protein phosphatase PP1-alpha catalytic subunit; PP-1A

Research area

Epigenetics and nuclear signaling; Tags & cell markers

Target protein

PPP1CA

Recommended dilution

Application Dilution
IF 1:100 - 1:500
WB 1:1000 - 1:2000

Images

Western Blot analysis using PP1Alpha Monoclonal antibody against HepG2. MCF7, HeLa cell lysate.
Immunofluorescence analysis of HeLa cells using PP1Alpha Monoclonal antibody.

Protocols

References

Customer reviews and Q&As

No reviews
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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

Add to Cart

Lead time: Within one week

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