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Home > Product > Antibody > Stat3 Monoclonal Antibody

Stat3 Monoclonal Antibody

Stat3 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human, Mouse, Monkey

Applications: WB, IHC-p, IF, ICC, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human,Mouse,Monkey

Applications: WB, IHC-p, IF, ICC, ELISA

Product overview

Full product name

Signal transducer and activator of transcription 3

Code

BT-MCA1163

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human Stat3 expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 6774; Mouse: 20848

Synonyms

STAT3; APRF; Signal transducer and activator of transcription 3; Acute-phase response factor

Research area

Signal transduction; Epigenetics and nuclear signaling; Cancer; Microbiology; Stem cells; Cardiovascular; Developmental biology

Target protein

STAT3

Recommended dilution

Application Dilution
ELISA 1:10000
IF 1:200 - 1:1000
IHC 1:200 - 1:1000
WB 1:500 - 1:2000

Images

Western Blot analysis using Stat3 Monoclonal antibody against HeLa (1)NIH/3T3 (2)Jurkat (3)PC-12 (4) and COS7 (5) cell lysate.
Immunohistochemistry analysis of paraffin-embedded mammary cancer tissues (left) and lung cancer tissues (right) with DAB staining using Stat3 Monoclonal antibody.
Immunofluorescence analysis of Hela cells using Stat3 Monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Protocols

References

Customer reviews and Q&As

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

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Lead time: Within one week

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