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Home > Product > Antibody > IGF-I Receptor beta(Phospho-Tyr1316) Rabbit Polyclonal Antibody

IGF-I Receptor beta(Phospho-Tyr1316) Rabbit Polyclonal Antibody

IGF-I Receptor beta(Phospho-Tyr1316) Rabbit Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: WB

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

Product overview

Full product name

IGF1RB

Code

BT-AP00414

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized phosho peptide around human IGF-I Receptor β (Tyr1316)

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Uniprot accession

Gene ID

Human: 3480; Mouse: 16001; Rat: 25718

Synonyms

IGF1RB; Insulin-like growth factor 1 receptor; EC 2.7.10.1; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain

Research area

Signal transduction; Cancer; Developmental biology

Target protein

IGF1R

Recommended dilution

Application Dilution
WB 1: 1000 - 1: 2000

Protocols

References

Customer reviews and Q&As

No reviews
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Product size

Price

  • 100ul

    $275.00

  • 50ul

    $180.00

  • 20ul

    $108.00

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Lead time: Within one week

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