Full product name
ADA11
Code
BT-AP00961
Host
Rabbit
Isotype
IgG
Size
100ul,50ul,20ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human ADA11
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.327% sodium azide.
Storage
-20°C for 1 year
Background
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Uniprot accession
Gene ID
Human: 4185; Mouse: 11488
Synonyms
ADA11; Disintegrin and metalloproteinase domain-containing protein 11; ADAM 11; Metalloproteinase-like; disintegrin-like; and cysteine-rich protein; MDC)
Research area
Signal transduction; Cancer; Cell biology
Target protein
ADAM11
