Cadherin-3

BT-AP01449

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human CDH3 Polyclonal

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS).

Human: P22223; Mouse: P10287;

Human: 1001; Mouse: 12560

Cadherin-3 (Placental cadherin;P-cadherin; Cadherin-3; Placental cadherin; P-cadherin

Cancer; Signal transduction; Tags & cell markers; Stem cells

CDH3