ATL2

BT-AP06186

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human ATL2

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.216% sodium azide.

-20°C for 1 year

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia.

Human: Q86TH1; Mouse: Q7TSK7;

Human: 9719; Mouse: 77794

ATL2; ADAMTS-like protein 2; ADAMTSL-2

Developmental biology; Signal transduction

ADAMTSL2