Seprase

BT-AP00682

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human FAP-1 Polyclonal

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Human: Q12884; Mouse: P97321;

Human: 2191; Mouse: 14089

Seprase (EC 3.4.21.-;170 kDa melanoma membrane-bound gelatinase;Fibroblast activation protein alpha;Integral membrane serine protease; Seprase; EC 3.4.21.-; 170 kDa melanoma membrane-bound gelatinase; Fibroblast activation protein alpha; Integral membrane serine protease)

Cancer

FAP