Fusin(Phospho Ser339) Polyclonal Antibody

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Home > Product > Antibody > Fusin(Phospho Ser339) Polyclonal Antibody

Fusin(Phospho Ser339) Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat, Monkey

Applications: WB, IHC-p, IF, ICC, ELISA

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat, Monkey

Applications: WB, IHC-p, IF, ICC, ELISA

Product overview

Full product name

C-X-C chemokine receptor type 4

Code

BT-AP00743

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human CXCR4 around the phosphorylation site of Ser339. AA range:303-352

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Uniprot accession

Human: P61073; Mouse: P70658; Rat: O08565;

Molecular weight

39746

Gene ID

Human: 7852; Mouse: 12767

Synonyms

C-X-C chemokine receptor type 4; CXCR4; C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; FB22; Fusin; HM89; LCR1; Leukocyte-derived seven transmembrane domain receptor; LESTR; NPYRL; Stromal cell-derived factor 1 receptor; SDF-1 receptor; CD antigen CD184

Research area

Cancer; Immunology; Metabolism; Microbiology; Neuroscience; Stem cells

Target protein

CXCR4

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IHC-p	1: 100 - 1: 300
IF	1: 200 - 1: 1000
ICC	1: 200 - 1: 1000
ELISA	1: 20000

Images

Immunofluorescence analysis of Hela cell. 1,Fusin (phospho Ser339) Polyclonal Antibody(Green) was diluted at 1:200(4°C overnight). 2 DAPI(blue) 10min.

Immunofluorescence analysis of HeLa cells, using CXCR4 (Phospho-Ser339) Antibody. The picture on the right is blocked with the phospho peptide.

Immunohistochemistry analysis of paraffin-embedded human brain, using CXCR4 (Phospho-Ser339) Antibody. The picture on the right is blocked with the phospho peptide.

Western Blot analysis of HuvEc etoposide 25uM 24H cells using Phospho-Fusin (S339) Polyclonal Antibody

Western blot analysis of lysates from HUVEC cells treated with etoposide 25uM 24H, using CXCR4 (Phospho-Ser339) Antibody. The lane on the right is blocked with the phospho peptide.

Protocols

> Protocol Booklet

References

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Datasheet

Product size

Price

100ul

$275.00
50ul

$180.00
20ul

$108.00

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Lead time: Within one week

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