CACNA1C

BT-AP06772

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human CACNA1C

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1| alpha-2/delta| beta| and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins| either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits.

Human: Q13936; Mouse: Q01815; Rat: P22002;

244310

Human: 775; Mouse: 12288; Rat: 24239

CACNA1C; Voltage-dependent L-type calcium channel subunit alpha-1C; Calcium channel; L type; alpha-1 polypeptide; isoform 1; cardiac muscle; Voltage-gated calcium channel subunit alpha Cav1.2

Cancer; Cardiovascular; Metabolism; Neuroscience; Signal transduction

CACNA1C