CATB

BT-AP06919

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human CATB (Cleaved-Asn126)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

Catalytic activity:Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase| shows peptidyl-dipeptidase activity| liberating C-terminal dipeptides.|Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.|Belongs to the peptidase C1 family.|subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.|subunit:Dimer of a heavy chain and a light chain cross-linked by a disulfide bond.|

Human: P07858; Mouse: P10605; Rat: P00787;

37290

Human: 1508; Mouse: 13030; Rat: 0

CATB ;Cleaved-Asn126; Cathepsin B; EC 3.4.22.1; APP secretase; APPS; Cathepsin B1; Cathepsin B light chain; Cathepsin B heavy chain;

Cancer; Neuroscience; Signal transduction

CTSB