Nuclear factor of activated T-cells| cytoplasmic 2

BT-AP07275

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthetic peptide from human protein at AA range: 640-700

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.

Human: Q13469; Mouse: Q60591;

Human: 4773; Mouse: 18019

Nuclear factor of activated T-cells; cytoplasmic 2;NF-ATc2;NFATc2;NFAT pre-existing subunit;NF-ATp;T-cell transcription factor NFAT1; Nuclear factor of activated T-cells; cytoplasmic 2; NF-ATc2; NFATc2; NFAT pre-existing subunit; NF-ATp; T-cell transcription factor NFAT1

Cancer; Cardiovascular; Epigenetics and nuclear signaling; Immunology; Metabolism; Signal transduction

NFATC2