NAD-dependent protein deacetylase sirtuin-1

BT-AP07980

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized phospho-peptide around the phosphorylation site of human SIRT1 (phospho Ser47)

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a member of the sirtuin family of proteins| homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however| yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.

Human: Q96EB6; Mouse: Q923E4;

81681

Human: 23411; Mouse: 93759

NAD-dependent protein deacetylase sirtuin-1; SIRT1; SIR2L1; NAD-dependent protein deacetylase sirtuin-1; hSIRT1; Regulatory protein SIR2 homolog 1; SIR2-like protein 1; hSIR2

Cell biology; Epigenetics and nuclear signaling; Metabolism; Microbiology; Tags & cell markers

SIRT1