Transforming growth factor beta-1

BT-AP08145

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human TGF β1 Polyclonal

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide| and is found in either a latent form composed of a mature peptide homodimer| a LAP homodimer| and a latent TGF-beta binding protein| or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation| differentiation and growth| and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene i

Human: P01137; Mouse: P04202; Rat: P17246;

Human: 7040; Mouse: 21803; Rat: 59086

Transforming growth factor beta-1 (TGF-beta-1) [Cleaved into: Latency-associated peptide (LAP)]; Transforming growth factor beta-1; TGF-beta-1; Latency-associated peptide; LAP;

Signal transduction; Stem cells; Cancer; Metabolism; Cardiovascular

TGFB1