COMP

BT-AP01791

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human COMP

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits| each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).

Human: P49747; Mouse: Q9R0G6; Rat: P35444;

83270

Human: 1311; Mouse: 12845; Rat: 25304

COMP

Cell biology; Signal transduction; Stem cells

COMP