SH3 domain-binding protein 2

BT-AP08360

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human protein . at AA range: 210-290

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain| an SH3-binding proline-rich region| and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases | and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T| natural killer (NK)| and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.

Human: P78314; Mouse: Q06649;

Human: 6452

SH3 domain-binding protein 2 ;3BP-2

Signal transduction

SH3BP2