Translation initiation factor IF-2, mitochondrial

BT-AP01982

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human protein . at AA range: 450-530

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

During the initiation of protein biosynthesis| initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is a single polypeptide| while eukaryotic cytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine liver mitochondria contain IF-2(mt)| an 85-kD monomeric protein that is equivalent to prokaryotic IF-2. The predicted 727-amino acid human protein contains a 29-amino acid presequence. Human IF-2(mt) shares 32 to 38% amino acid sequence identity with yeast IF-2(mt) and several prokaryotic IF-2s| with the greatest degree of conservation in the G domains of the proteins.

Human: P46199; Mouse: Q91YJ5;

Human: 4528

Translation initiation factor IF-2; mitochondrial ;IF-2;Mt;IF-2Mt;IF2;mt

Epigenetics and nuclear signaling

MTIF2