Eukaryotic translation initiation factor 6

BT-AP08661

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human protein . at AA range: 180-260

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4)| a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein| which is insoluble and found both in the nucleus and in the cytoplasm| can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene.

Human: P56537; Mouse: O55135; Rat: Q3KRD8;

Human: 3692

Eukaryotic translation initiation factor 6 (eIF-6;B(2)GCN homolog;B4 integrin interactor;CAB;p27(BBP))

Epigenetics and nuclear signaling; Neuroscience

EIF6