Dab1

BT-AP08877

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human Dab1 (Phospho Tyr220)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.|Adapter molecule functioning in neural development. May regulate SIAH1 activity.|PTM:Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.|Contains 1 PID domain.|subunit:Associates with the SH2 domains of SRC| FYN and ABL. Interacts with DAB2IP and SIAH1 (By similarity). Interacts with LRP1.|

Human: O75553; Mouse: P97318; Rat: Q8CJH2;

64680

Human: 1600; Mouse: 13131; Rat: 266729

Dab1 ;Phospho Tyr220; Disabled homolog 1

Neuroscience; Signal transduction

DAB1